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{"id":1414,"date":"2015-12-18T15:06:42","date_gmt":"2015-12-18T15:06:42","guid":{"rendered":"http:\/\/www.delanyco.com\/?p=1414"},"modified":"2016-11-16T11:25:47","modified_gmt":"2016-11-16T11:25:47","slug":"yesterdays-disrupters-are-todays-modern-conveniences-microbiology","status":"publish","type":"post","link":"https:\/\/www.delanyco.com\/2015\/12\/18\/yesterdays-disrupters-are-todays-modern-conveniences-microbiology\/","title":{"rendered":"Yesterday\u2019s Disrupters are Today\u2019s Modern Conveniences: Microbiology"},"content":{"rendered":"

In the Middle Ages, the recipe to make\u00a0mice called for a pair of dirty underwear and some wheat grain. Yes, that\u2019s right, you could mix up your overdue laundry with some wheat and you\u2019d be guaranteed a bucket of critters in 21 days or less. The implications of putting wheat kernels in your pants no doubt horrified the public at the time.\u00a0<\/span><\/p>\n

\"mice\"<\/a><\/span><\/p>\n

Francesco Redi disproved this in 1668 with experiments using meat and maggots. He illustrated that if you leave a steak on a table, but covered it in cheesecloth, flies wouldn\u2019t land on it and maggots would not appear.<\/span><\/p>\n

Over the next two hundred years, the public accepted that animals you could see were born, bred, or hatched. The idea that there were living things you couldn\u2019t see acting the same way took a little longer to catch on. When the 19<\/span>th<\/span> century rolled around, the leading scientific powers in Paris were ready to put this idea of \u2018Spontaneous Generation\u2019 to bed.<\/span><\/p>\n

However, things were not going to go according to their plan.<\/span><\/p>\n

\"Screen<\/a>F\u00e9lix Archim\u00e8de Pouchet published <\/span>Heterogenie<\/span><\/i> in 1859\u2013 a report about a series of experiments with chicken broth where he claimed that when you boiled broth to kill microbes (the little micro-organisms that breed in food when it goes off) they would regenerate themselves from nothing and\/or \u2018the hand of God\u2019.<\/span><\/p>\n

This was regarded as a step backward. The whole mice thing had been disproven and the French were now hoping someone would find a new way to explain the birth of the squiggly moving shapes scientists observed under their microscopes.<\/span><\/p>\n

Enter: Louis Pasteur credited with pasteurization, modern day vaccinations and microbiology. \u00a0Sharing the stage: \u00a0a regulating body offering fame and hard cold cash for some alternative proof.<\/span><\/p>\n

French science was regulated. Formal Commissions were assigned to listen and adjudicate when scientists published papers or argued with prevailing truths.<\/span><\/p>\n

The Academie des Sciences was Paris\u2019s scientific version of the European Commission and it was dead set against the idea of \u2018Spontaneous Generation\u2019. The Academie offered 2,500 francs to whomever \u2018by well conducted experiments throws new light on the question of so-called spontaneous generations\u2019.\"Screen<\/a> <\/span><\/p>\n

Louis Pasteur, already a well-known personality in these circles, stepped up to the game, but he was already the house bet.<\/span><\/p>\n

You assume that there is a benign wind that separates the wheat from the chaff, especially when science is involved. But in some cases, having a regulatory body means your science wins, whether it lives up to the scientific method, or not.<\/span><\/p>\n

Six men were initially appointed to the Academie\u2019s commission that would decide who won the argument about \u2018Spontaneous Generation\u2019. Two had announced their decision against Poulet\u2019s experiments before they read Poulet\u2019s paper or saw his evidence. One person on the commission, Antoine Balard, was not only Pasteur\u2019s tutor, but it has been said that he helped Pasteur come up with the winning idea.<\/span><\/p>\n

\"flask\"<\/a>Regardless of the fact that Louis Pasteur was no scientific underdog whose heroic discovery mastered adversity, his famous swan neck flask experiments did the job.<\/span><\/p>\n

Pasteur filled a flask with chicken broth, but then heated and re-shaped the neck of the flask so no air could reach the broth once it had been (pasteurized) boiled. \u00a0Any microbes in the air got caught in the neck of the flask and the broth stayed clear of microbes, finally putting to rest \u2018Spontaneous Generation\u2019 and garnering Pasteur the 2,500 francs.<\/span><\/p>\n

Questions about scientific process still linger for Pasteur, whose laboratory notes were finally released a century after his experiments. \u00a0They illustrate a political operator who stole ideas, lied about experimental evidence and even, in the famous case of his rabies vaccine, tested on a young boy before he had conclusive evidence from his animal subjects. \u00a0Not only did Pasteur have all the plaudits, he also had all the coin. At one point, he received 10% of all government grants in France to run his famous foundation.<\/span><\/p>\n

The French government was lucky in that Louis Pasteur had a lifelong habit of being right.<\/span><\/p>\n

At the end of the day, the good guy won because, he achieved progress despite using the right science. \u00a0<\/span><\/p>\n

Right?<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

In the Middle Ages, the recipe to make\u00a0mice called for a pair of dirty underwear and some wheat grain. Yes, that\u2019s right, you could mix up your overdue laundry with some wheat and you\u2019d be guaranteed a bucket of critters in 21 days or less. The implications of putting wheat kernels in your pants no […]<\/p>\n","protected":false},"author":6,"featured_media":1448,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[82,80,81,77,83],"yoast_head":"\nYesterday\u2019s Disrupters are Today\u2019s Modern Conveniences: Microbiology - Delany & Co<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.delanyco.com\/2015\/12\/18\/yesterdays-disrupters-are-todays-modern-conveniences-microbiology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Yesterday\u2019s Disrupters are Today\u2019s Modern Conveniences: Microbiology - Delany & Co\" \/>\n<meta property=\"og:description\" content=\"In the Middle Ages, the recipe to make\u00a0mice called for a pair of dirty underwear and some wheat grain. 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